Month: June 2021

June 30, 2021

• Ultra-fast, less than one-minute scan time, cardiac MRI enables accurate assessment of heart anatomy and function, improves patient comfort, increases access to care, and reduces costs
• Technique can be implemented on existing MRI scanners
• Validated clinical trial results on more than 100 patients with diverse cardiac pathologies published in leading journal JACC: Cardiovascular Imaging

Amsterdam, the Netherlands and Madrid, Spain – Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, has participated in an important research project to develop a magnetic resonance (MR) imaging technique [1,2] that could potentially revolutionize the use of MR imaging in cardiology.

Reducing the procedure time for full evaluation of heart anatomy and function from about one hour down to a few minutes, this new technique has the potential to increase patient access to precision diagnosis, improve patient comfort due to shorter scan times, and lower the cost of care. The technique can be used with existing phased-array MRI scanners without modification. The results of a clinical trial to evaluate the technique [2] were published in April, 2021, in JACC (Journal of the American College of Cardiology): Cardiovascular Imaging, one of the world’s highest impact journals in the field [3].

“In just over 20 seconds, all the information needed to know the shape and function of the heart has been acquired. And if you need to evaluate the degree of fibrosis after cardiac muscle death, another 20-second acquisition is all it takes, completing the cardiac study in less than a minute,” said Philips scientist Dr. Javier Sánchez-González, technical leader of the Philips team that contributed to the development and leader of the collaboration with CNIC.

During a conventional MR cardiac examination, patients are required to lie still inside the bore of the scanner for about one hour to accurately measure the function of their heart and assess the extent of damaged heart muscle. It requires multiple complex 2D and 3D image acquisitions that need to be captured and reconstructed. As a result, despite being non-invasive and involving no radiation exposure, MR imaging is still not widely used for cardiac imaging.

“The main cause is the time needed to do a full study. A complete study requires about an hour, a period that causes many patients not to finish the test due to the discomfort it causes them,” said Dr. Sandra Gómez-Talavera, researcher at the Spanish National Center for Cardiovascular Research (CNIC), cardiologist at the Hospital Universitario Fundación Jiménez Díaz (Madrid, Spain), and co-author of the JACC paper.

The new technique (called ‘Enhanced SENSE by Static Outer-volume Subtraction (ESSOS)) makes use of the fact that during a breath-hold, everything within the patient’s chest remains static, except their beating heart. After an initial image of the static part (outer volume) has been captured this MRI data is temporarily removed. The MRI signal of the beating heart can now more easily be subtracted from subsequent scan data, allowing up to four times faster acquisition of a 3D image of the heart. This results in a net acceleration factor of up to 32. Once the dynamic information of the beating heart is reconstructed, the static outer volume images are added back to generate a full 3D cardiac image showing heart anatomy and function, and allowing review from different views with good image resolution. If needed, a second contrast-enhanced isotropic 3D single breath-hold scan can reveal the extent of damage to the patient’s heart muscle.

The results of a clinical trial in which more than 100 patients with various cardiac pathologies were examined using both the conventional and the new MR protocol, with the resulting images being evaluated by expert radiologists, demonstrated excellent agreement between heart function measurements made using each technique, as well as excellent agreement in the images to characterize tissue damage to the patient’s heart muscle [4].

“We have shown in a large group of patients that cardiac MR imaging using this new technology obtains the same parameters as the usual technique but reduces the time that a patient has to be inside the machine by more than 90%,” said Dr. Borja Ibáñez, Director of the Clinical Research Department of CNIC, Cardiologist at the University Hospital Fundación Jiménez Díaz, and clinical leader of the work.

The research project to develop this new cardiac MR protocol was financed by the Carlos III Institute of Health, through a FIS technological development project, as well as a Translational Research Grant from the Spanish Society of Cardiology, the European Research Council (ERC), and the Community of Madrid.

While the collaboration between CNIC and Philips is currently at the research stage, the goal is to bring this ultra-fast and easy cardiac MR technique to clinical settings in the near future and support the common vision of benefiting more patients. Already today Philips’ integrated MR solutions offer new levels of ultra-fast and personalized cardiac MR. Examples include the company’s exam-shortening Compressed SENSE technology, ultra-fast early diagnosis of heart failure with Strain–encoded magnetic resonance imaging (SENC-MRI) and MyoStrain (by Myocardial Solutions), SmartWorkflow end-to-end workflow solution, and helium-free scanners. Learn more at MR Cardiac imaging | Philips Healthcare.

More information on the new magnetic resonance (MR) imaging technique can be found in this press backgrounder.

[1] ‘Enhanced SENSE by Static Outer-volume Subtraction’ (ESSOS)
[2] Device for research applications only. Not for clinical use.
[3] Comparison of the Impact Factors of the Most-Cited Cardiovascular Journals | Circulation Research (ahajournals.org); Impact Factor Results Rank JACC Journals Among Top 12 Cardiovascular Journals Worldwide – American College of Cardiology
[4] Gómez-Talavera S, Fernandez-Jimenez R, Fuster V, Nothnagel ND, Kouwenhoven M, Clemence M, García-Lunar I, Gómez-Rubín MC, Navarro F, Pérez-Asenjo B, Fernández-Friera L, Calero MJ, Orejas M, Cabrera JA, Desco M, Pizarro G, Ibáñez B, Sánchez-González J. (2021). Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences.  JACC Cardiovasc Imaging, doi: 10.1016/j.jcmg.2021.02.03

For further information, please contact:

For Philips:
Kathy O’Reilly
Philips Global Press Office
Tel.: +1 978-221-8919
E-mail : kathy.oreilly@philips.com
Twitter: @kathyoreilly

For CNIC:
Fatima Lois
Head of Communications of the CNIC. flois@cnic.es
Tel.: +34 6 39 28 24 77
E-mail: flois@cnic.es

About Royal Philips
Royal Philips (NYSE: PHG, AEX: PHIA) is a leading health technology company focused on improving people’s health and well-being, and enabling better outcomes across the health continuum – from healthy living and prevention, to diagnosis, treatment and home care. Philips leverages advanced technology and deep clinical and consumer insights to deliver integrated solutions. Headquartered in the Netherlands, the company is a leader in diagnostic imaging, image-guided therapy, patient monitoring and health informatics, as well as in consumer health and home care. Philips generated 2020 sales of EUR 17.3 billion and employs approximately 77,000 employees with sales and services in more than 100 countries. News about Philips can be found at www.philips.com/newscenter.

About CNIC
The National Center for Cardiovascular Research (CNIC), led by Dr. Valentín Fuster, has as its mission to enhance cardiovascular research and its translation to the patient. The center is financed by a pioneering formula of public-private collaboration between the Government of Spain, through the Carlos III Institute of Health, and the Pro CNIC Foundation that brings together 12 of the most important Spanish companies.

Attachments

• Press backgrounder Philips CNIC ultra-fast MR protocol
• Philips MR scanner
• Philips MR scanner
• Ultra Fast 3C CMR protocol

VICTOR, N.Y., June 30, 2021 (GLOBE NEWSWIRE) — Constellation Brands, Inc. (NYSE: STZ and STZ.B), a leading beverage alcohol company, reported today its first quarter fiscal 2022 results. A conference call to discuss the financial results and outlook will be hosted by President and Chief Executive Officer Bill Newlands and Chief Financial Officer Garth Hankinson on Wednesday, June 30, 2021, at 11:30 a.m. (EDT).

Visit cbrands.com/investors/events to locate information for joining the conference call, or a live, listen-only webcast of the conference call.

ABOUT CONSTELLATION BRANDS

At Constellation Brands (NYSE: STZ and STZ.B), our mission is to build brands that people love because we believe sharing a toast, unwinding after a day, celebrating milestones, and helping people connect, are Worth Reaching For. It’s worth our dedication, hard work, and the bold calculated risks we take to deliver more for our consumers, trade partners, shareholders, and communities in which we live and work. It’s what has made us one of the fastest-growing large CPG companies in the U.S. at retail, and it drives our pursuit to deliver what’s next.

Today, we are a leading international producer and marketer of beer, wine, and spirits with operations in the U.S., Mexico, New Zealand, and Italy. Every day, people reach for our high-end, iconic imported beer brands such as Corona Extra, Corona Light, Corona Premier, Modelo Especial, Modelo Negra, and Pacifico, and our high-quality premium wine and spirits brands, including the Robert Mondavi Brand Family, Kim Crawford, Meiomi, The Prisoner Brand Family, SVEDKA Vodka, Casa Noble Tequila, and High West Whiskey.

But we won’t stop here. Our visionary leadership team and passionate employees from barrel room to boardroom are reaching for the next level, to explore the boundaries of the beverage alcohol industry and beyond. Join us in discovering what’s Worth Reaching For.

To learn more, follow us on Twitter @cbrands and visit www.cbrands.com.

MEDIA CONTACTS	INVESTOR RELATIONS CONTACTS
Mike McGrew 773-251-4934 / michael.mcgrew@cbrands.com Amy Martin 585-678-7141 / amy.martin@cbrands.com	Patty Yahn-Urlaub 585-678-7483 / patty.yahn-urlaub@cbrands.com Marisa Pepelea 312-741-2316 / marisa.pepelea@cbrands.com

A PDF containing our First Quarter Fiscal Year 2022 Results and full financial tables is available at: http://ml.globenewswire.com/Resource/Download/fbfd501f-76ca-4f23-8679-6e117020105e

MONTREAL, June 30, 2021 (GLOBE NEWSWIRE) — Brunswick Exploration Inc. (“BRW” or the “Company”) is pleased to announce that it has received necessary permits to begin drilling at its Lac Édouard nickel-copper-cobalt project (“Lac Édouard”), located 40 km northeast of the town of La Tuque, Quebec, and 125 km northwest of Quebec City. An initial 3,000 meters program is planned over the month of July. Drilling will target the down-dip potential to the north of the known mineralization as well as an elongated geophysical (EM) anomaly stretching 540 metres to the east of the deposit.

Furthermore, Company staff have identified mineralized float (glacial boulders) of peridotite hosting nickel-copper sulphide mineralization located 1,900 metres northwest of the Lac Édouard deposit as well as 3,900 metres south of the deposit. Assays are pending and will be released when available.

Mr. Killian Charles, President of BRW, commented: “We are very excited about advancement of the Lac Édouard project and the potential for discovering new high-grade nickel-copper-cobalt sulphide mineralization. The mineralization near the deposit is open at a shallow depth and has been undrilled since the early 1970’s. Furthermore, the historical mineralization was never assayed for platinum, palladium or cobalt. We are also excited to see work advance across our portfolio of projects in New Brunswick and Quebec with further drilling to begin later this year.”

Additional Exploration Updates:

New Brunswick

• Fundy Gold (Gold-Silver-Copper): BRW’s seasoned exploration team has been prospecting since early May both regionally and following up on the December 2020 high grade gold-in-soil anomalies (see news release dated March 16th); multiple assays are pending and will be released as they are received. A regional, 500 metres space gold-in-till program is expected to be completed by late July. The program will allow the Company to focus its prospecting work across key areas of interest.
• Bathurst Mining Camp (Zinc-Lead-Copper-Silver VMS): The newly completed geological model along the Brunswick Belt from Brunswick No.12 to Gilmour South has been combined and integrated with a new model from Gilmour South to Key Anacon, covering a total strike length of approximately 72 kilometres. Several drill targets have been identified and BRW is planning a 1,500-2,500m drill program to test coincident geophysical and geological anomalies that correspond to the preferred stratigraphy that hosted the prolific Brunswick No.12 in late summer 2021.

Quebec

• Waconichi (Zinc-Lead-Copper-Silver VMS): an airborne gravity gradiometry survey was recently flown across the property. Following interpretation of the new data, the Company has identified 5 high-priority coincident gravity and EM anomalies. These anomalies have never been drilled and BRW plans to test the targets in the fall of 2021.

Qualified Person

The scientific and technical information contained in this press release has been reviewed and approved by Mr. Robert Wares, P. Geo, CEO of Brunswick Exploration.

About Brunswick Exploration

The Company is a Montreal-based mineral exploration venture listed on the TSX-V under symbol BRW. The Company is now focused on exploration and development of gold and base metal properties in Eastern Canada. Current projects include gold-polymetallic vein systems in Southern New Brunswick (Fundy Gold Project), the Lac Édouard nickel-copper project in Québec, base metals VMS in the Bathurst Camp in New Brunswick and in the Chibougamau region of Quebec (Waconichi).

Investor Relations/Information

Mr. Killian Charles, President (info@BRWexplo.com).

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release

Cautionary Statement on Forward-Looking Information

This news release contains “forward-looking information” within the meaning of applicable Canadian securities legislation based on expectations, estimates and projections as at the date of this news release. Forward-looking information involves risks, uncertainties and other factors that could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information. Factors that could cause actual results to differ materially from such forward-looking information include, but are not limited to, delays in obtaining or failures to obtain required governmental, environmental or other project approvals; uncertainties relating to the availability and costs of financing needed in the future; changes in equity markets; inflation; fluctuations in commodity prices; delays in the development of projects; the other risks involved in the mineral exploration and development industry; and those risks set out in the Corporation’s public documents filed on SEDAR at www.sedar.com. Although the Corporation believes that the assumptions and factors used in preparing the forward-looking information in this news release are reasonable, undue reliance should not be placed on such information, which only applies as of the date of this news release, and no assurance can be given that such events will occur in the disclosed time frames or at all. The Corporation disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, other than as required by law. Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release.

Images are projected over the Swiss Alps as part of a launch event for Genesis Motor Europe at Lauterbrunnen, Switzerland

Further assets can be downloaded here.

• Luxury carmaker Genesis reveals biggest-ever projection of its kind in the Swiss Alps, signalling its arrival in Europe and set in stone a commitment to rewriting the rules of car ownership
• Stunning mountain scenery of the Swiss Alps transformed with latest 3D mapping technology to create a spectacular display the size of almost three football pitches
• Genesis promises new approach to car buying and ownership with exceptional customer service and respect for everyone

LAUTERBRUNNEN, Switzerland, June 30, 2021 (GLOBE NEWSWIRE) — Last night, luxury carmaker Genesis created the largest-ever 3D projection of its kind on a mountain in the Swiss Alps, to mark the brand’s arrival in Europe.

The projection confirmed the car brand’s commitment to changing the way people buy and own cars in Europe, by promising the ‘Genesis Difference’, a set of principles to respect every customer’s time and provide exceptional customer service. These promises were ‘set in stone’ through the magic of the cutting-edge projection technology.

Lighting up the cliff-face of a mountain near Lauterbrunnen, the spectacular display measured an impressive 275m wide and 180m high and was brought to life via a state-of-the-art 3D projection, seamlessly merging high-tech and nature.

Media and VIPs witnessed a dazzling show started by the projection of two lines – synonymous with Genesis’ design language – which seemingly broke through the mountain’s surface, bringing the rough canvas of the rockface to life.

The projection continued with the mountain’s surface intruding, to reveal the impression of a brightly lit space. As anticipation grew, guests were finally able to cast their eyes on images of the Genesis vehicles, appearing on the mountain at around 30 times the size of an average two story house.

At the final crescendo, the iconic Genesis logo was revealed, marking the brand’s arrival in Europe. Carving a commitment to treat all customers with respect and to change the way the car industry looks at customer service, into the Swiss Alps. To watch the animation, please visit https://www.youtube.com/channel/UCaWpwCpuVoMPSVl82yw4eJA.

The projection marks the start of business for the Genesis brand in Europe, beginning with customers in the UK, Germany and Switzerland.

Car buyers can expect a very different experience with Genesis Personal Assistants in every Genesis Studio; staff who are focused on delivering high quality service instead of sales. Pricing is fixed, no matter if you buy in the Studio, or online; no more haggling. If the customer wants a test drive, Genesis will come to them, delivering a car to their home or work, respecting their time.

Dominique Boesch, Managing Director, Genesis Motor Europe, commented: ‘‘The ‘Genesis Difference’ is a modern approach to car buying and ownership that gives all drivers an effortless option, we place exceptional customer experience over sales.

“We offer a car buying and ownership experience which is stress free and saves your time.

“At Genesis, our Korean heritage underpins everything we do, from design and innovation to our service, rooted in the Korean principles of hospitality and respect. By taking care of the details so our customers don’t have to, we give them the most precious luxury – their time.

“We are making a promise to our customers that we will do things differently.”

Notes to editors

For more information, please contact:

M&C Saatchi Talk: genesis@mcsaatchi.com

Genesis Europe Media Centre
www.genesisnewseurope.com

Genesis Europe Comms Twitter
@genesis_eu_pr

Genesis Twitter and Instagram
@genesis_europe

Genesis Facebook
www.facebook.com/GenesisEuropeGmbH

Genesis Linkedin
www.linkedin.com/company/genesis-motor-europe

About Genesis
Following its launch in 2015, Genesis has established itself as a true alternative within the premium segment. With a commitment to hospitality and great service, Genesis strives to build sincere relationships with customers and above all, to respect the greatest luxury of all – their time. The brand was launched first in South Korea and following success in the U.S., Canada, Russia, the Middle East and Australia, Genesis has set its sights on Europe and China. Embodying its unique design language ‘Athletic Elegance’, the brand continues to strengthen its range of vehicles and services to appeal to a broader range of consumers. The first electric car, the Genesis G80, will launch this year, with more to follow. Genesis is one of the highest-ranked brands in the automotive industry by respected third-party experts including North American Car of the Year, Consumer Reports and J.D. Power. Genesis is the only brand with a full product range to achieve IIHS Top Safety Pick+.

For more information on Genesis and its definition of premium, please visit www.genesis.com. Please visit our media site for the latest global news at http://genesisnewseurope.com/ and Twitter at @genesis_eu_pr.

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/3c556086-bc7a-4b5b-a3d8-f7a7dcec9355

“The photo is also available at Newscom, www.newscom.com, and via AP PhotoExpress.”

NEW YORK, June 29, 2021 (GLOBE NEWSWIRE) — LiquidX, the global fintech solutions provider for working capital, trade finance, and insurance today announced that its Singapore entity, LiquidX Insurance Services (Singapore) Pte. Ltd. (LISS), has received approval from the Monetary Authority of Singapore (MAS) to offer insurance brokerage services in the country. Alex Bursak, Director and Regional Head of Insurance Asia Pacific at LiquidX, was named Director of the program.

LISS can now help banks, asset managers and funds, and corporates of all sizes in Singapore to access, automate, and streamline Trade Credit Insurance coverage via the LiquidX 360 platform. The digital platform serves the entire Trade Credit Insurance value chain for quoting, policy management, and risk monitoring. LiquidX 360 is the only solution that integrates Trade Credit Insurance with next-generation capabilities for buying, selling, and managing Accounts Receivable and other trade finance assets on the same platform.

The Trade Credit Insurance market is estimated to roughly double in size from 2021 to 2027, from $9 to 18 billion, due to its role of mitigating trade risk in uncertain economic environments. By 2025, LiquidX estimates that between 30% – 50% of Trade Credit Insurance will be originated, managed, and transacted online. The LiquidX 360 proprietary platform will fuel a significant portion of this online growth.

“The MAS license is a huge milestone for our business in Asia,” said Jim Toffey, CEO of LiquidX. “With a growing market for Trade Credit Insurance, carriers and brokers are looking to technology to scale their growth, cut expenses, and digitally connect with their partners and policyholders. In addition, funders and corporates that manage and finance working capital on our platform can now seamlessly integrate Trade Credit Insurance coverage. We are thrilled that our technology is making the whole trade ecosystem run more efficiently.”

“We are honored and excited to be registered as an insurance broker by MAS, which will allow us to strengthen our position as the global leader in digitizing the Trade Credit Insurance market. As a key trading and finance hub in Asia, Singapore will continue to be an accelerator for our best-in-class tech-focused LiquidX 360 platform,” said Alex Bursak, Director and Regional Head of Insurance Asia Pacific at LiquidX.

About LiquidX

LiquidX is a leading global technology company that enables finance professionals to transact faster, smarter, and cheaper by digitizing and automating their trade finance and working capital management. Headquartered in New York with offices in Boston, London, and Singapore, LiquidX delivers the industry-leading ecosystem for working capital optimization to its diverse network of global participants including corporations, banks, institutional investors, and insurance providers. LiquidX incorporates blockchain technology and machine learning analytics to greatly enhance transparency, reporting, and forecasting for financial professionals. To learn more about our next generation solutions please visit liquidx.com.

Media Contact:		Sue Hinton
		LiquidX (New York)
		shinton@liquidx.com | +1 917-362-4518